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49ers can knock Rams down a peg tonight

If the San Francisco 49ers beat the Indianapolis Colts on Monday, the Los Angeles Rams will slip from the 5 seed to the 6 seed in the NFC playoff picture. It’s a remarkable turnaround from where these teams were at going into their Week 5 matchup — an overtime win by the 49ers — and […]

From Turf Show Times | 28 days ago | 0 reads

49ers vs. Colts: Monday Night Football Game Discussion

The Indianapolis Colts host the San Francisco 49ers in Indy. These teams are on vastly different trajectories, as the Niners are on a four-game winning streak and Indy is on a four-game losing streak. Will San Francisco make it five-straight? Can Indy avoid five-straight? Let’s tune in to find out! San Francisco 49ers at Indianapolis Colts Lucas […]

From Canal Street Chronicles | 28 days ago | 0 reads

49ers-Colts game thread: Tonight will come down to red zone execution

For all of the talk about how the San Francisco 49ers still need to win. And despite playing a quarterback who is projected to throw for 159 yards tonight, this will not be an easy game. The Indianapolis Colts have several weapons at Philip Rivers’ disposal, and the best one is at running back. Jonathan […]

From Niners Nation | 28 days ago | 0 reads

Buffalo Bills fan discussion: Playoff picture chat with Indianapolis Colts on ‘Monday Night Football’

After tonight, there’s just two weeks left on the 2025 NFL regular-season schedule. To wrap up Week 16, we get a Monday Night Football matchup between the Indianapolis Colts and San Francisco 49ers that should hold everyone’s interests. If you’re looking for Buffalo Bills-related playoff rooting interests, the task is simple: With a Colts loss, […]

From Buffalo Rumblings | 28 days ago | 2 reads

49ers vs. Colts: Monday Night Football

Week 16 of the 2025 NFL season ends tonight with a Monday Night Football game between the San Francisco 49ers and Indianapolis Colts. The Philadelphia Eagles’ chances of getting the No. 1 seed are incredibly slim (like, 0.1% chance slim) but the Birds will remain mathematically alive for a first-round bye if the 49ers lose […]

From Bleeding Green Nation | 28 days ago | 1 read

49ers vs. Colts live discussion: Philip Rivers can help the Seahawks

Okay, so Philip Rivers almost had a dream comeback after ending his five-year retirement to play for the Indianapolis Colts. The Seattle Seahawks thwarted Rivers with an 18-16 victory thanks to six Jason Myers field goals. Philip Rivers is 4-0 against the San Francisco 49ers. A win for the Colts at home on Monday Night […]

From Field Gulls | 28 days ago | 0 reads

49ers at Colts, Week 16 MNF fan discussion

Week 16 comes to a close with a “Monday Night Football” matchup featuring the San Francisco 49ers (10-4) and the Indianapolis Colts (8-6). The 49ers have clinched a playoff berth in the NFC Playoffs—the Detroit Lions can only hope to tie their record, and San Francisco holds the tie-breaker, so they’re in—but they’re still fully […]

From Pride Of Detroit | 28 days ago | 1 read

Monday Night Football: Colts vs. 49ers – Lineups, Broadcast Info, Game Thread, More

Week 16 concludes this evening, with the Colts taking on the 49ers on Monday Night Football. How to Watch Monday Night Football: Colts vs. 49ers TV: ABC Streaming: NFL+ Radio: Westwood One Kickoff Time: 7:15 PM CT Site: Lucas Oil Stadium, Indianapolis, IN. Referee: Ron Torbert Odds : 49ers -5.5, O/U 45.5 ( via DraftKings Sportsbook ) Kevin Ng-Imagn Images Colts Projected Starters Offense QB  – Philip Rivers RB  – Jonath...

From Bleacher Nation | Chicago Sports News, Rumors, and a Reasonable Level of Obsession | 28 days ago | 0 reads

bet365 Bonus Code BNATION Earns $150 for Monday Night Football and More

Monday night brings some solid sports action, and a bet365 bonus code can be used for any matchup. This gets you $150 in bonus bets for games like the 49ers taking on the Colts. bet365 Bonus Code BNATION New users can register with the bonus code BNATION to score the bonus. Sign up with BNATION on bet365. 21+ to wager (18+ in Kentucky). Geolocation confirms if you can bet in your state. Make a deposit. Place a $5 bet… First wager must be -500 od...

From Bleacher Nation | Chicago Sports News, Rumors, and a Reasonable Level of Obsession | 28 days ago | 0 reads

Where to Watch: 49ers at Colts for MNF

The Indianapolis Colts (8-6) host the San Francisco 49ers (10-4) on primetime (8:15 PM EST) trying to keep their late season playoff hopes alive. Having lost 5 of their last 6 games, it’s desperation time in Indy. Entering the evening, the Colts average the league’s 6th most points (28.0 avg. ppg.) and surrender its 13th […]

From Stampede Blue | 28 days ago | 2 reads

49ers vs Colts Spread, Game Odds, and More for Monday Night Football

Monday Night Football brings an interconference matchup that puts the San Francisco 49ers on the road against the Indianapolis Colts. This game matters for playoff positioning and momentum, and the betting market reflects a competitive but clearly defined matchup. You are looking at a spread under a touchdown, a mid-range total, and moneylines that suggest one team holds the edge but still faces risk away from home. Below is a full betting-focused preview designed to help you evaluate the...

From Bleacher Nation | Chicago Sports News, Rumors, and a Reasonable Level of Obsession | 28 days ago | 0 reads

NFL DFS Picks for 49ers vs Colts Including Christian McCaffrey & Jonathan Taylor on BN Fantasy for MNF Week 16

Monday Night Football delivers another exciting game with the 49ers vs Colts battling for playoff positioning. Both teams boast good lineups that offer numerous NFL DFS options on BN Fantasy . The 49ers have one of the league’s most dangerous players in Christian McCaffrey. Meanwhile, the Colts will lean on their own star runner, Jonathan Taylor with Philip Rivers making his 2nd start. To make the night more exciting, BN Fantasy has a couple of awesome promos available for new users. Firs...

From Bleacher Nation | Chicago Sports News, Rumors, and a Reasonable Level of Obsession | 28 days ago | 1 read

Colts activate DeForest Buckner from injured reserve

Indianapolis, IN — The Indianapolis Colts have received a big-time reinforcement ahead of their Monday Night Football matchup against the San Francisco 49ers. Star defensive tackle DeForest Buckner (neck) has officially been activated from the injured reserve list after missing the last five games, a fitting return to the limelight as this is Indy’s first […]

From Stampede Blue | 28 days ago | 5 reads

49ers-Colts numbers to know: Kyle Shanahan gets a favorable matchup tonight

With the San Francisco 49ers winning their last four games against what may be the easiest stretch of their schedule, they turn around to begin the toughest stretch of their schedule with a Monday night tilt against the Indianapolis Colts. A few weeks ago, this game against Indianapolis was trending towards being a matchup between […]

From Niners Nation | 28 days ago | 1 read

Philip Rivers Passing Props and Odds as 44-Year-Old Takes on the 49ers on MNF

The wildest storyline of the NFL season continues tonight as 44-year-old quarterback Philip Rivers will start at quarterback for the second straight week for the Colts. Check out his passing props and odds for tonight’s Monday Night Football game between the 49ers and Colts. $250 deposit bonus for NFL pick’em contests! Philip Rivers Passing Props (Rivers played his first game since 2020 last week. Photo: Kevin Ng-Imagn Images) The Colts shocked the world last week when they...

From Bleacher Nation | Chicago Sports News, Rumors, and a Reasonable Level of Obsession | 28 days ago | 0 reads

Kalshi Promo Code BNATION Scores $10 Bonus on 49ers vs Colts and More Prediction Markets

New users can score a Kalshi promo code to make trades on prediction markets like Monday Night Football’s matchup between the 49ers and Colts. Here is how to get your $10 bonus. Kalshi Promo Code BNATION Use the Kalshi promo code BNATION to earn a $10 bonus after making $100 in trades. Sign up with Kalshi using BNATION. 18+ to use Kalshi. Make a deposit. Make $100 of trades on markets like sports, politics, and more. Score a $10 bonus. How Much ...

From Bleacher Nation | Chicago Sports News, Rumors, and a Reasonable Level of Obsession | 28 days ago | 0 reads

Jaguars vs Colts: Week 17 opening odds

The Jacksonville Jaguars (11-4) will fly from the Rocky Mountains to the Midwest to face the Indianapolis Colts (8-6 at the time of this writing) at 1:00 p.m. EST on Sunday, Dec. 28. According to FanDuel Sportsbook, the Jaguars are 6.5-point favorites and the total is set at 45.5 points. The Colts play tonight on […]

From Big Cat Country | 28 days ago | 0 reads

Chargers open up as betting favorites ahead of Week 17 vs. Texans

The Los Angeles Chargers are coming off a big win against Dak Prescott and the Dallas Cowboys in Week 16, getting one step closer to a playoff berth. The Chargers can officially clinch a playoff spot if the San Francisco 49ers beat the Indianapolis Colts on Monday Night Football, but they will also do so […]

From Bolts From The Blue | 29 days ago | 0 reads

BetMGM Bonus Code BLEACHNEWS Scores $1,500 Bonus Including 49ers vs Colts

New users can score a BetMGM bonus code for a $1,500 offer, including games like the 49ers taking on the Colts. Here is what you need to do. BetMGM Bonus Code BLEACHNEWS Use the BetMGM bonus code BLEACHNEWS for a $1,500 first bet offer. Your first wager is covered by bonus bets if you lose. Register with BLEACHNEWS. 21 or older to use BetMGM. Must be in a BetMGM legal state. Make your first deposit. Bet up to $1,500 on your first wager. If you don...

From Bleacher Nation | Chicago Sports News, Rumors, and a Reasonable Level of Obsession | 29 days ago | 0 reads